Format guide

NIfTI viewer for iPhone and iPad: open .nii and .nii.gz files

Ossidex opens NIfTI-1 files (.nii and gzip-compressed .nii.gz) on iPhone and iPad. It applies the orientation stored in the file, including sheared affines, shows the volume in 2D, MPR and 3D, and displays label maps and segmentation masks as layers you can toggle per segment.

Download on the App StoreFree to download · iPhone & iPad · iOS 17+
MRI volume viewed in linked panels in Ossidex on iPad

What NIfTI is

NIfTI (Neuroimaging Informatics Technology Initiative) is a research format for volumetric data, widely used in neuroimaging and machine-learning pipelines (for example segmentation outputs). Unlike DICOM, one .nii file holds the whole volume and a compact header with voxel size and orientation, but little patient or scanner detail.

Supported

FeatureStatus
NIfTI-1 .nii and .nii.gzYes
Orientation from sform/qform, including shearYes
Label maps / masks as overlay layersYes
Per-segment visibilityYes
NIfTI-2Not yet
4D NIfTI and float overlaysNot yet

Open a NIfTI file

  1. Save the file. Put the .nii or .nii.gz (and any mask files) in Files, or share a link.
  2. Import. Tap + → Files in Ossidex and select the files.
  3. View. The volume opens; masks appear as layers with a toggle for each segment.

NIfTI vs DICOM at a glance

DICOMNIfTI-1
Typical useClinical imaging and archivingResearch, analysis, AI pipelines
Files per volumeOften one per sliceOne file (.nii or .nii.gz)
Patient and study metadataExtensiveMinimal
OrientationPer image position/orientation tagsqform/sform matrices
SegmentationsDICOM SEG, RTSTRUCTLabel-map volumes

NIfTI viewers by platform

ViewerPlatformPriceBest for
MRIcroGLWindows, macOS, LinuxFreeQuick viewing and rendering of research volumes
ITK-SNAPWindows, macOS, LinuxFree, open sourceManual and semi-automatic segmentation
3D SlicerWindows, macOS, LinuxFree, open sourceSegmentation, registration and analysis
FSLeyesmacOS, Linux (part of FSL)Free for non-commercial useNeuroimaging analysis output
NiiVue / PapayaWeb browserFree, open sourceViewing in a browser without installing
OssidexiPhone, iPadFree download; Pro for MPR and 3DViewing volumes and masks on a phone or tablet

Desktop research tools remain the right place for analysis; Ossidex is for looking at a volume or a segmentation away from the computer.

Opening NIfTI step by step on iPad

  1. Collect the files. Put the image volume and its mask files in one folder in Files, or zip them.
  2. Import the folder. Tap + → Files in Ossidex and select the folder or ZIP.
  3. Toggle segments. Open the layers panel to show or hide each labelled structure over the image.

Typical NIfTI sources

SourceExample
Neuroimaging researchBrain MRI converted from DICOM with dcm2niix
Segmentation toolsLabel maps from 3D Slicer, ITK-SNAP or nnU-Net
Public datasetsChallenge datasets and open research collections
AI pipelinesModel outputs saved as masks next to the input volume

Masks as layers

Import the image volume together with its mask files. Ossidex recognises label maps and shows them as coloured overlays; each segment gets its own visibility toggle, so you can show one structure at a time. Masks follow the same orientation as the volume, including sheared affines, which is where many simple viewers draw overlays in the wrong place.

Orientation, explained briefly

A NIfTI header stores how voxel indices map to patient space (the qform and sform matrices). Viewers that ignore them show the volume flipped or rotated. Ossidex applies the stored transform and labels directions (left/right, anterior/posterior, superior/inferior) accordingly.

Limits

NIfTI files contain little clinical metadata — no patient name, study date or scanner details — so the study appears under the file name. NIfTI-2, 4D time series and floating-point overlay maps are not supported yet.

Frequently asked questions

Can I view a segmentation from 3D Slicer or nnU-Net?

If it is saved as NIfTI-1 label map, yes — it appears as a layer over the image volume.

Is NIfTI better than DICOM?

They serve different purposes: DICOM is the clinical standard with full metadata; NIfTI is a compact research format.

Can I measure on NIfTI volumes?

Yes. Distances use the voxel size stored in the NIfTI header, in millimetres, on slices and MPR planes.

Where do I get NIfTI files from DICOM?

Research tools such as dcm2niix convert DICOM series to NIfTI. For clinical viewing you do not need to convert — Ossidex opens the original DICOM.

Can I convert NIfTI back to DICOM in Ossidex?

No. Ossidex opens NIfTI for viewing and exports images or PDF, not DICOM.

Does .nii.gz need unpacking first?

No. Gzip-compressed NIfTI is read directly.

Sources

Related pages

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